PhD Position in Hydrogen/Deuterium Exchange Mass Spectrometry to Study the Regulation of Lipoprotein Lipase

Job title: PhD Position in Hydrogen/Deuterium Exchange Mass Spectrometry to Study the Regulation of Lipoprotein Lipase

Company: Syddansk Universitet


Job description: Job Category: PH.D.Job Description:Do you want to join one of the strongest biomedical mass spectrometry research environments in Europe? Here is an excellent opportunity to work on an exciting and challenging project in such an environment.The Jørgensen group at the / at the at the University of Southern Denmark (SDU) is looking for a highly motivated PhD student to join a project on elucidating the mechanisms by which endogenous activators and inhibitors regulate lipoprotein lipase using hydrogen deuterium exchange mass spectrometry (HDX-MS).This is a highly interdisciplinary project with nine investigators with expertise in different research fields working in six institutions in six countries. You will be part of an international and dynamic research team. You will be motivated to use advanced HDX-MS to investigate the regulation of lipoprotein lipase. You will manage an independent research project and assist in the supervision of undergraduate students.The Jørgensen group is part of the / at BMB and offers a strong international research environment in proteomics, protein chemistry, biomolecular mass spectrometry, and computational proteomics.Qualifications
We are looking for a highly motivated and enthusiastic candidate with excellent communication skills.For consideration, applicants must have:

• A recent Master’s degree in biochemistry, protein science/proteomics, analytical biochemistry or a related field
• Experience in experimental protein biochemistry and mass spectrometry
• Excellent English speaking, reading and writing skills

In addition, applicants with practical experience with HDX-MS and/or LC-MS/MS will be preferred.A recent publication of ours on lipoprotein lipase studied by HDX-MS is: Kumari et al., ANGPTL3/8 is an atypical unfoldase that regulates intravascular lipolysis by catalyzing unfolding of lipoprotein lipase. Proc. Natl. Acad. Sci. U.S.A., 122, e2420721122 (2025)Place of work: Protein Research Group (Assoc. Prof. Thomas J.D. Jørgensen), Department of Biochemistry and Molecular Biology, University of Southern Denmark, Odense, DenmarkApplication deadline: July 1, 2025 at 23:59 hours local Danish time. Preferred start date: September 1, 2025For further information, contact: Associate Professor Thomas J.D. JørgensenApplication, salary etc.
Appointment as a PhD Research Fellow is for three years. Employment stops automatically at the end of the period.( ).Further information about the PhD programme at the Faculty of Science can be found at the .The University wishes our staff to reflect the diversity of society and thus welcomes applications from all qualified candidates regardless of personal background.Application must be in English and made in the form of a Declaration of Interest including the following:

• Copies of diplomas, Bachelor as well as Master’s degree, including transcript of notes/grades (if Master’s diploma has not yet been received, please include statement from your supervisor)
• Contact details (phone numbers and e-mail) for at least 2 referees who can vouch for your skills.
• A letter stating your specific interest, motivation, and qualifications for the project in question (max. two pages) .
• Detailed CV, including personal contact information and date entries

Shortlisting may be used in the assessment process. Incomplete applications and applications received after the deadline will neither be considered nor evaluated. This also applies to reference letters.Applications will be assessed by an expert assessor/committee. Applicants will be informed of their assessment by the university.Applications should be sent electronically via the link “Apply now”. The faculty expects applicants to read the information ” ” before applying. Please note that the application documents should be in pdf-format and attached as three documents: motivation letter, CV and the remaining documents.We recommend that as an international applicant you take the time to visit where you will find information and facts about moving to, working and living in Denmark, as well as the .

Expected salary:

Location: Odense, Syddanmark

Job date: Wed, 04 Jun 2025 00:58:13 GMT

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